Development

Production

Veterinary Drugs Sales

Development

Production

Veterinary Drugs Sales

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Организация: 
Название организации*
Отзыв: 
My kitty refuses to eat any medicine. I found out that there is an inexpensive (in comparison with foreign-made) medicine against worms with a meaty taste. When the time came to give the pill, I mixed it into a dry feed and offered it to the hungry cat in the morning for breakfast. The cat ate it without noticing anything. The problem with the use of anthelmintics has been resolved. A big thanks to the manufacturer!
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Отзыв: 
I thank the manufacturer for the drug. I give tablets to my Abyssinian cat regularly, because we often travel by car together. Leaving the animal at home does not work for me. And without a sedative in the car, the cat panics. The problem with panic was solved with Express Uspokoin. The cat now rides in the car in silence. And I'm not worried about my cat’s nervous system.
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Supramil for cats weighing from 2 kg

A superpill for a superpet.

The principle of the action

The active components of the drug R-praziquantel and milbemycin oxime provide its wide spectrum of anthelmintic action.

Milbemycin oxime is a macrocyclic lactone obtained as a result of the enzymatic activity of Streptomyces hygroscopicus var. Aureolacrimosus, is active against larvae and imago of nematodes parasitizing in the gastrointestinal tract of cats, as well as larvae of the nematode Dirofilaria immitis.

The mechanism of action of milbemycin is due to an increase in the permeability of cell membranes for chloride ions (Cl-), which leads to overpolarization of the membranes of nerve and muscle tissue cells, paralysis and death of sensitive nematodes. The maximum plasma concentration of milbemycin oxime in cats is reached within 2 hours; bioavailability is about 80%. The compound is excreted from the body mainly unchanged.

R-praziquantel (levorotatory optical isomer) is a compound of the pyrazinisoquinoline group, its mechanism of action is based on inducing the decay of tegument, persistent depolarization of helminth muscle cells, disruption of energy metabolism, which causes paralysis and death of cestodes, and promotes their excretion from the gastrointestinal tract. R-praziquantel is rapidly absorbed in the gastrointestinal tract, reaching its maximum concentration in the blood plasma after 1-3 hours, reversibly binds to serum proteins (70-80%), partially metabolized in the liver, re-excreted into the intestine, excreted from the body mainly with urine (up to 80%) within 24 hours.

The use of active R-praziquantel in the composition of the preparation (instead of the racemic mixture of optical isomers of R-praziquantel and S praziquantel) made it possible to reduce the concentration of the compound while maintaining a high level of cestodicidal activity.

Supramil tablets are classified as low-hazard substances in terms of their impact on the body (hazard class 4 according to GOST 12.1.007); in recommended doses does not have a sensitizing, embryotoxic and teratogenic effect.

The drug is toxic to bees, as well as fish and other aquatic organisms.

Composition of the drug

R-praziquantel, milbemycin.

Contraindications

Contraindications to the use of Supramil tablets are the increased individual sensitivity of the animal to the components of the drug, including a history, severe renal and liver dysfunction.

Emaciated animals sick with infectious diseases, cats weighing less than 0.5 kg, kittens under 6 weeks old are not subject to deworming.

Drug form

Pills.

Period of validity

The shelf life of the medicinal product, subject to storage conditions in the manufacturer's sealed packaging, is 3 years from the date of production.

Do not use Supramil tablets beyond the expiration date.

Storage conditions

Store Supramil tablets in the manufacturer's sealed packaging, protected from light, separate from food and feed, at a temperature not exceeding 25 C.

Keep Supramil tablets out of the reach of children.

Product line

Where buy

Организация: 
Название организации*
Отзыв: 
An elderly cat has experienced the loss of its owner. Now she lives with me. It’s a cat of a Persian breed. It is terrified of loud noises: a vacuum cleaner, even flushing water in the toilet (if nearby), and the fireworks. When it hears claps, hum, explosions of firecrackers, the cat hides somewhere or under the sofa, refuses to eat, and may not leave its shelter for hours. I gave the cat Express Uspokoin on New Year's holidays, when fireworks exploded periodically for days. I gave the drug for 3 days in a row. The cat behaved calmly. It ate and drank as usual, and used the toilet. I am glad that with the help of the drug the cat managed to live a normal life during such a difficult time.
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Supramil for kittens and cats weighing up to 2 kg

A superpill for a superpet

The principle of the action

The active components of the drug R-praziquantel and milbemycin oxime provide its wide spectrum of anthelmintic action.

Milbemycin oxime is a macrocyclic lactone obtained as a result of the enzymatic activity of Streptomyces hygroscopicus var. Aureolacrimosus, is active against larvae and imago of nematodes parasitizing in the gastrointestinal tract of cats, as well as larvae of the nematode Dirofilaria immitis.

The mechanism of action of milbemycin is due to an increase in the permeability of cell membranes for chloride ions (Cl-), which leads to overpolarization of the membranes of nerve and muscle tissue cells, paralysis and death of sensitive nematodes. The maximum plasma concentration of milbemycin oxime in cats is reached within 2 hours; bioavailability is about 80%. The compound is excreted from the body mainly unchanged.

R-praziquantel (levorotatory optical isomer) is a compound of the pyrazinisoquinoline group, its mechanism of action is based on inducing the decay of tegument, persistent depolarization of helminth muscle cells, disruption of energy metabolism, which causes paralysis and death of cestodes, and promotes their excretion from the gastrointestinal tract. R-praziquantel is rapidly absorbed in the gastrointestinal tract, reaching its maximum concentration in the blood plasma after 1-3 hours, reversibly binds to serum proteins (70-80%), partially metabolized in the liver, re-excreted into the intestine, excreted from the body mainly with urine (up to 80%) within 24 hours.

The use of active R-praziquantel in the composition of the preparation (instead of the racemic mixture of optical isomers of R-praziquantel and S praziquantel) made it possible to reduce the concentration of the compound while maintaining a high level of cestodicidal activity.

Supramil tablets are classified as low-hazard substances in terms of their impact on the body (hazard class 4 according to GOST 12.1.007); in recommended doses does not have a sensitizing, embryotoxic and teratogenic effect.

The drug is toxic to bees, as well as fish and other aquatic organisms.

Composition of the drug

R-praziquantel, milbemycin.

Contraindications

Contraindications to the use of Supramil tablets are the increased individual sensitivity of the animal to the components of the drug, including a history, severe renal and liver dysfunction.

Drug form

Pills.

Period of validity

The shelf life of the medicinal product, subject to storage conditions in the manufacturer's sealed packaging, is 3 years from the date of production.

Do not use Supramil tablets beyond the expiration date.

Storage conditions

Store Supramil tablets in the manufacturer's sealed packaging, protected from light, separate from food and feed, at a temperature not exceeding 25 C.

Keep Supramil tablets out of the reach of children.

Product line

Where buy

Express Uspokoin for cats 6 tablets

Express Uspokoin. A quick overcoming of anxiety and stress.

 

 

 

 

The principle of the action

Succinate, a triazolopyridine derivative, which is part of the drug trazodone, is an antagonist of alpha1-adenoreceptors, having sedative and anxiolytic effects, reduces the severity or suppresses the manifestation of fear, anxiety, somatic symptoms of anxiety: heart palpitations, salivation, excessive, locomotor activity, vocalization , destructive behavior, has a calming effect, reduces tension.

The mechanism of action of trazodone succinate is associated with its high affinity for subtypes A and C of 5-HT serotonin receptors, with which it enters into antagonistic or agonistic interactions, depending on the subtype, as well as with a specific ability to induce inhibition of serotonin reuptake.

Absorption of trazodone from the gastrointestinal tract after oral administration is high. Taking the drug during or immediately after feeding slows down the absorption rate of trazodone, reduces its concentration in blood plasma and prolongs the time to reach the maximum concentration. Trazodone penetrates the histohematogenous barriers, as well as into tissues and fluids (bile, saliva, milk), is metabolized in the liver to form metabolites, including the active metabolite, m-chlorophenylpiperazine. It is excreted from the body mainly in the form of inactive metabolites, mainly in the urine (about 75%) and partially in the bile.

In rare cases, when the drug is taken for the first time, the animal may experience drowsiness and impaired coordination of movements, which spontaneously pass and do not require the use of drugs. With repeated use, these side effects are not observed.

Composition of the drug

Trazodone succinate.

Contraindications

Contraindications for use are: increased individual sensitivity of the animal to the components of the drug, including a history, impaired liver and kidney function, diseases of the cardiovascular system and epilepsy.

Do not use the drug in females during pregnancy and breastfeeding, as well as in newborn kittens.

Drug form

Pills.

Period of validity

The shelf life of the medicinal product, subject to storage conditions in the manufacturer's sealed packaging, is 3 years from the date of production.

Express Uspokoin tablets should not be used after the expiration date.

Storage conditions

Store Uspokoin Express tablets in the manufacturer's closed packaging, protected from light, separate from food and feed, at a temperature not exceeding 25 ° C.

Express Uspokoin tablets should be kept out of the reach of children.

Product line

Where buy

Express Uspokoin for cats 2 tablets

Express Uspokoin. A quick overcoming of anxiety and stress.

 

 

 

 

The principle of the action

Succinate, a triazolopyridine derivative, which is part of the drug trazodone, is an antagonist of alpha1-adenoreceptors, having sedative and anxiolytic effects, reduces the severity or suppresses the manifestation of fear, anxiety, somatic symptoms of anxiety: heart palpitations, salivation, excessive, locomotor activity, vocalization , destructive behavior, has a calming effect, reduces tension.

The mechanism of action of trazodone succinate is associated with its high affinity for subtypes A and C of 5-HT serotonin receptors, with which it enters into antagonistic or agonistic interactions, depending on the subtype, as well as with a specific ability to induce inhibition of serotonin reuptake.

Absorption of trazodone from the gastrointestinal tract after oral administration is high. Taking the drug during or immediately after feeding slows down the absorption rate of trazodone, reduces its concentration in blood plasma and prolongs the time to reach the maximum concentration. Trazodone penetrates the histohematogenous barriers, as well as into tissues and fluids (bile, saliva, milk), is metabolized in the liver to form metabolites, including the active metabolite, m-chlorophenylpiperazine. It is excreted from the body mainly in the form of inactive metabolites, mainly in the urine (about 75%) and partially in the bile.

In rare cases, when the drug is taken for the first time, the animal may experience drowsiness and impaired coordination of movements, which spontaneously pass and do not require the use of drugs. With repeated use, these side effects are not observed.

Composition of the drug

Trazodone succinate.

Contraindications

Contraindications for use are: increased individual sensitivity of the animal to the components of the drug, including a history, impaired liver and kidney function, diseases of the cardiovascular system and epilepsy.

Do not use the drug in females during pregnancy and breastfeeding, as well as in newborn kittens.

Drug form

Pills.

Period of validity

The shelf life of the medicinal product, subject to storage conditions in the manufacturer's sealed packaging, is 3 years from the date of production.

Express Uspokoin tablets should not be used after the expiration date.

Storage conditions

Store Uspokoin Express tablets in the manufacturer's closed packaging, protected from light, separate from food and feed, at a temperature not exceeding 25 ° C.

Express Uspokoin tablets should be kept out of the reach of children.

Product line

Where buy

Организация: 
ветеринарный врач частной практики, г. Самара
Отзыв: 
For several years now I have been using BlohNet for preventive treatment of animals in my private practice. Every year from April to November (treatment is carried out monthly) no flea infestation is observed, the animals do not itch and feel great. The BlohNet drug completely suits me and my pets, and I will use it in the future.
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In March 2013, a domestic Persian cat was treated with the Vermidine preparation due to the presence of worms in the feces of the animal. The cat swallowed the pill easily. After that, there were no signs of infection in the cat. Vermidin has helped us.
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Отзыв: 
I learned about the Vermidine tablets from the veterinarian who examined my cat. The doctor recommended using this remedy before vaccination. I was told that these are quite effective pills, they will help to free the cat's body from worms or conduct a prophylaxis. I bought Vermidin tablets at a veterinary pharmacy and gave them to the cat 10 days before vaccination. I put the tablet on the root of the tongue, and the cat immediately swallowed it. I did not observe any changes in the pet's well-being. The drug is of completely satisfactory quality.
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